| Patrick Leahy Burlington International → Chicago O'Hare International BTV–ORD | 1,230 | 123,641 | 83% | 763 | United Air Lines Inc., SkyWest Airlines Inc., Envoy Air, Republic Airline | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Washington Dulles International BTV–IAD | 1,199 | 60,230 | 81% | 441 | GoJet Airlines LLC d/b/a..., CommuteAir LLC dba CommuteAir, Republic Airline, Mesa Airlines Inc. +2 | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Newark Liberty International BTV–EWR | 1,103 | 56,891 | 79% | 266 | Republic Airline, GoJet Airlines LLC d/b/a..., United Air Lines Inc., Federal Express Corporation +2 | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Ronald Reagan Washington Ntl BTV–DCA | 1,091 | 69,751 | 80% | 437 | PSA Airlines Inc., American Airlines Inc., Republic Airline, Envoy Air | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Philadelphia International BTV–PHL | 1,073 | 75,045 | 83% | 335 | PSA Airlines Inc., American Airlines Inc., Republic Airline | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Detroit Metro Wayne County BTV–DTW | 763 | 47,081 | 84% | 537 | Endeavor Air Inc., SkyWest Airlines Inc., Delta Air Lines Inc. | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Laguardia BTV–LGA | 688 | 38,750 | 75% | 258 | Endeavor Air Inc., Republic Airline | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → John F Kennedy International BTV–JFK | 686 | 38,298 | 74% | 266 | Endeavor Air Inc. | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Charlotte/Douglas International BTV–CLT | 628 | 42,052 | 87% | 761 | PSA Airlines Inc., American Airlines Inc. | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Hartsfield/Jackson Atlanta International BTV–ATL | 378 | 49,067 | 82% | 961 | Delta Air Lines Inc. | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Syracuse Hancock International BTV–SYR | 250 | 47 | 64% | 175 | Federal Express Corporation, Tradewind Aviation, Piedmont Airlines | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Denver International BTV–DEN | 213 | 31,445 | 89% | 1,639 | United Air Lines Inc. | May 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Minneapolis-St Paul Intl/Wold-Chamberlain BTV–MSP | 163 | 12,624 | 87% | 987 | Endeavor Air Inc., Sun Country Airlines d/b/a..., Delta Air Lines Inc., SkyWest Airlines Inc. +1 | Jun 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Raleigh-Durham International BTV–RDU | 138 | 15,424 | 82% | 663 | Breeze Aviation Group DBA Breeze | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Orlando International BTV–MCO | 128 | 14,174 | 76% | 1,194 | Breeze Aviation Group DBA Breeze, Frontier Airlines Inc. | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Tampa International BTV–TPA | 103 | 11,284 | 82% | 1,250 | Breeze Aviation Group DBA Breeze | Jan 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Charleston Afb/Intl BTV–CHS | 62 | 6,847 | 82% | 880 | Breeze Aviation Group DBA Breeze, USA Jet Airlines Inc. | May 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Southwest Florida International BTV–RSW | 44 | 4,861 | 81% | 1,326 | Breeze Aviation Group DBA Breeze | Jan 2025 – May 2026 |
| Patrick Leahy Burlington International → Patrick Leahy Burlington International BTV–BTV | 16 | 0 | 0% | 0 | SkyWest Airlines Inc. | Mar 2025 – Jun 2026 |
| Patrick Leahy Burlington International → Teterboro BTV–TEB | 12 | 38 | 38% | 254 | Tradewind Aviation, LIMA NY Corp d/b/a Fly The Whale, Air Hamburg... | Jan 2025 – Jun 2026 |
| Patrick Leahy Burlington International → George Bush Intcntl/Houston BTV–IAH | 10 | 606 | 85% | 1,570 | Mesa Airlines Inc. | May 2026 – Jul 2026 |
| Patrick Leahy Burlington International → Westchester County BTV–HPN | 7 | 25 | 45% | 237 | Tradewind Aviation | Jan 2025 – Jun 2026 |
| Patrick Leahy Burlington International → Martha'S Vineyard BTV–MVY | 7 | 17 | 30% | 249 | Tradewind Aviation | Feb 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Indianapolis International BTV–IND | 6 | 3 | 4% | 750 | Federal Express Corporation, Republic Airline | Jun 2025 – Mar 2026 |
| Patrick Leahy Burlington International → Montreal BTV–YUL international | 4 | 221 | 90% | 75 | Piedmont Airlines, Endeavor Air Inc., Republic Airline | May 2025 – Jun 2026 |
| Patrick Leahy Burlington International → Albany International BTV–ALB | 3 | 5 | 21% | 123 | Tradewind Aviation | Jan 2025 – Dec 2025 |
| Patrick Leahy Burlington International → Bishop International BTV–FNT | 3 | 0 | 0% | 540 | SkyWest Airlines Inc. | Aug 2025 – May 2026 |
| Patrick Leahy Burlington International → Lehigh Valley International BTV–ABE | 2 | 118 | 94% | 288 | Endeavor Air Inc., GoJet Airlines LLC d/b/a... | Mar 2026 – Mar 2026 |
| Patrick Leahy Burlington International → Nantucket Memorial BTV–ACK | 2 | 6 | 38% | 272 | Tradewind Aviation | Jul 2025 – Dec 2025 |
| Patrick Leahy Burlington International → Wilkes-Barre/Scranton International BTV–AVP | 2 | 126 | 83% | 252 | PSA Airlines Inc., Republic Airline | Aug 2025 – Aug 2025 |
| Patrick Leahy Burlington International → MC Ghee Tyson BTV–TYS | 2 | 273 | 86% | 827 | Delta Air Lines Inc. | Dec 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Ottawa BTV–YOW international | 2 | 87 | 87% | 136 | GoJet Airlines LLC d/b/a... | Apr 2025 – Jul 2026 |
| Patrick Leahy Burlington International → Waterloo Regional BTV–ALO | 1 | 0 | 0% | 974 | SkyWest Airlines Inc. | Jul 2026 – Jul 2026 |
| Patrick Leahy Burlington International → Laurence G Hanscom Field BTV–BED | 1 | 2 | 25% | 167 | Tradewind Aviation | Jan 2025 – Nov 2025 |
| Patrick Leahy Burlington International → Bangor International BTV–BGR | 1 | 52 | 68% | 214 | Endeavor Air Inc. | Sep 2025 – Sep 2025 |
| Patrick Leahy Burlington International → Block Island State BTV–BID | 1 | 4 | 50% | 242 | Tradewind Aviation | Aug 2025 – Aug 2025 |
| Patrick Leahy Burlington International → General Edward Lawrence Logan International BTV–BOS | 1 | 127 | 99% | 181 | American Airlines Inc. | Jul 2025 – Aug 2025 |
| Patrick Leahy Burlington International → Akron-Canton Regional BTV–CAK | 1 | 106 | 77% | 488 | Breeze Aviation Group DBA Breeze | Jul 2026 – Jul 2026 |
| Patrick Leahy Burlington International → Lovell Field BTV–CHA | 1 | 128 | 97% | 912 | Delta Air Lines Inc. | Jan 2026 – Jan 2026 |
| Patrick Leahy Burlington International → Cleveland-Hopkins International BTV–CLE | 1 | 148 | 89% | 489 | United Air Lines Inc. | Jan 2025 – Aug 2025 |
| Patrick Leahy Burlington International → City Of Colorado Springs Municipal BTV–COS | 1 | 129 | 78% | 1,668 | United Air Lines Inc. | May 2026 – May 2026 |
| Patrick Leahy Burlington International → Dubrovnik BTV–DBV international | 1 | 6 | 43% | 4,334 | VistaJet Limited | Sep 2025 – Sep 2025 |
| Patrick Leahy Burlington International → Durango-La Plata County BTV–DRO | 1 | 149 | 90% | 1,868 | United Air Lines Inc. | Jun 2026 – Jun 2026 |
| Patrick Leahy Burlington International → Danbury Municipal BTV–DXR | 1 | 3 | 38% | 215 | Tradewind Aviation | Feb 2026 – Feb 2026 |
| Patrick Leahy Burlington International → Fishers Island BTV–FID | 1 | 2 | 25% | 229 | Tradewind Aviation | Jun 2026 – Jun 2026 |
| Patrick Leahy Burlington International → Grand Junction Regional BTV–GJT | 1 | 149 | 99% | 1,848 | United Air Lines Inc. | Jun 2025 – Aug 2025 |
| Patrick Leahy Burlington International → Greenville Spartanburg International BTV–GSP | 1 | 134 | 84% | 817 | Delta Air Lines Inc. | Nov 2025 – Nov 2025 |
| Patrick Leahy Burlington International → East Hampton BTV–HTO | 1 | 5 | 62% | 247 | Tradewind Aviation | Jun 2026 – Jun 2026 |
| Patrick Leahy Burlington International → Tweed/New Haven BTV–HVN | 1 | 0 | 0% | 222 | TEM Enterprises dba Avelo Airlines | May 2025 – Mar 2026 |
| Patrick Leahy Burlington International → Long Island Mac Arthur BTV–ISP | 1 | 86 | 63% | 254 | Breeze Aviation Group DBA Breeze | Mar 2026 – Mar 2026 |
| Patrick Leahy Burlington International → Kansas City International BTV–MCI | 1 | 0 | 0% | 1,164 | SkyWest Airlines Inc. | Jun 2026 – Jun 2026 |
| Patrick Leahy Burlington International → Frederick W Smith Intl/Memphis BTV–MEM | 1 | 0 | | 1,104 | Federal Express Corporation | Jun 2025 – Feb 2026 |
| Patrick Leahy Burlington International → Morristown Municipal BTV–MMU | 1 | 5 | 62% | 262 | Tradewind Aviation | Jun 2026 – Jun 2026 |
| Patrick Leahy Burlington International → Sullivan County International BTV–MSV | 1 | 3 | 38% | 208 | Tradewind Aviation | Jul 2026 – Jul 2026 |
| Patrick Leahy Burlington International → Okc Will Rogers International BTV–OKC | 1 | 0 | 0% | 1,434 | SkyWest Airlines Inc. | Jun 2026 – Jun 2026 |
| Patrick Leahy Burlington International → St. Pete-Clearwater International BTV–PIE | 1 | 5 | 62% | 1,258 | CFM Inc d/b/a Contour... | Feb 2026 – Feb 2026 |
| Patrick Leahy Burlington International → Pittsburgh International BTV–PIT | 1 | 0 | 0% | 454 | Republic Airline | Jan 2025 – May 2026 |
| Patrick Leahy Burlington International → Chicago Executive BTV–PWK | 1 | 4 | 50% | 760 | Scott Aviation, LLC d/b/a... | Oct 2025 – Oct 2025 |
| Patrick Leahy Burlington International → Rapid City Regional BTV–RAP | 1 | 150 | 100% | 1,476 | United Air Lines Inc. | Jun 2025 – Aug 2025 |
| Patrick Leahy Burlington International → Griffiss International BTV–RME | 1 | 3 | 38% | 141 | Tradewind Aviation | Oct 2025 – Oct 2025 |
| Patrick Leahy Burlington International → Louisville Muhammad Ali International BTV–SDF | 1 | 100 | 56% | 784 | Allegiant Air | Mar 2026 – Mar 2026 |
| Patrick Leahy Burlington International → Tri-Cities BTV–TRI | 1 | 76 | 100% | 735 | PSA Airlines Inc. | Jul 2025 – Jun 2026 |
| Patrick Leahy Burlington International → Van Nuys BTV–VNY | 1 | 3 | 25% | 2,495 | Scott Aviation, LLC d/b/a... | Mar 2026 – Mar 2026 |
| Patrick Leahy Burlington International → Quebec BTV–YQB international | 1 | 47 | 94% | 181 | Piedmont Airlines | Jul 2026 – Jul 2026 |
| Patrick Leahy Burlington International → Toronto BTV–YTZ international | 1 | 1 | 17% | 316 | Hamilton Jetport Limited | May 2026 – May 2026 |