| Mobile Regional → Hartsfield/Jackson Atlanta International MOB–ATL | 1,685 | 127,648 | 84% | 302 | Endeavor Air Inc., Delta Air Lines Inc., SkyWest Airlines Inc., Piedmont Airlines | Jan 2025 – Jul 2026 |
| Mobile Regional → George Bush Intcntl/Houston MOB–IAH | 1,442 | 62,872 | 86% | 427 | CommuteAir LLC dba CommuteAir, Mesa Airlines Inc., Republic Airline | Jan 2025 – Jul 2026 |
| Mobile Regional → Dallas-Fort Worth International MOB–DFW | 1,106 | 64,928 | 79% | 539 | Envoy Air, PSA Airlines Inc. | Jan 2025 – Jul 2026 |
| Mobile Regional → Charlotte/Douglas International MOB–CLT | 1,036 | 43,993 | 84% | 526 | Piedmont Airlines, PSA Airlines Inc. | Jan 2025 – Jul 2026 |
| Mobile Regional → Washington Dulles International MOB–IAD | 479 | 20,307 | 85% | 836 | CommuteAir LLC dba CommuteAir | Jan 2025 – Jul 2026 |
| Mobile Regional → Pensacola International MOB–PNS | 10 | 540 | 73% | 65 | Envoy Air, Endeavor Air Inc., CommuteAir LLC dba CommuteAir, PSA Airlines Inc. +1 | Mar 2025 – Jul 2026 |
| Mobile Regional → Birmingham-Shuttlesworth International MOB–BHM | 2 | 208 | 95% | 216 | Delta Air Lines Inc. | Nov 2025 – Jul 2026 |
| Mobile Regional → Fort Wayne International MOB–FWA | 2 | 0 | 0% | 729 | SkyWest Airlines Inc., Sun Country Airlines d/b/a... | Aug 2025 – Jan 2026 |
| Mobile Regional → Jackson-Medgar Wiley Evers International MOB–JAN | 2 | 121 | 96% | 155 | Endeavor Air Inc., Piedmont Airlines | Jan 2025 – Jun 2026 |
| Mobile Regional → Reno/Tahoe International MOB–RNO | 2 | 109 | 29% | 1,875 | Sun Country Airlines d/b/a... | Aug 2025 – Nov 2025 |
| Mobile Regional → Shreveport Regional MOB–SHV | 2 | 97 | 66% | 351 | PSA Airlines Inc., SkyWest Airlines Inc. | Jun 2025 – May 2026 |
| Mobile Regional → Eglin Afb/Destin-Ft Walton Beach MOB–VPS | 2 | 98 | 64% | 103 | Envoy Air, PSA Airlines Inc. | Jan 2026 – Mar 2026 |
| Mobile Regional → Augusta Regional AT Bush Field MOB–AGS | 1 | 50 | 100% | 412 | Piedmont Airlines | Jul 2025 – Jan 2026 |
| Mobile Regional → Austin-Bergstrom International MOB–AUS | 1 | 75 | 99% | 564 | PSA Airlines Inc. | Apr 2025 – Mar 2026 |
| Mobile Regional → Baton Rouge Metro, Ryan Field MOB–BTR | 1 | 101 | 92% | 174 | Delta Air Lines Inc. | Jun 2025 – Jun 2026 |
| Mobile Regional → Baltimore/Washington International Thurgood Marshall MOB–BWI | 1 | 135 | 84% | 878 | Eastern Air Express, LLC (EAX) | Aug 2025 – Aug 2025 |
| Mobile Regional → Columbia Metro MOB–CAE | 1 | 47 | 94% | 473 | Piedmont Airlines | Apr 2025 – Jun 2026 |
| Mobile Regional → Lovell Field MOB–CHA | 1 | 70 | 92% | 348 | Endeavor Air Inc. | Aug 2025 – Aug 2025 |
| Mobile Regional → Charlottesville-Albemarle MOB–CHO | 1 | 49 | 98% | 758 | CommuteAir LLC dba CommuteAir | May 2026 – May 2026 |
| Mobile Regional → Easterwood Field MOB–CLL | 1 | 68 | 89% | 484 | Envoy Air | May 2026 – May 2026 |
| Mobile Regional → John Glenn Columbus International MOB–CMH | 1 | 0 | 0% | 709 | Sun Country Airlines d/b/a... | Oct 2025 – Oct 2025 |
| Mobile Regional → Fayetteville Rgnl/Grannis Field MOB–FAY | 1 | 46 | 92% | 619 | Piedmont Airlines | Jun 2026 – Jun 2026 |
| Mobile Regional → Greenville Spartanburg International MOB–GSP | 1 | 49 | 98% | 455 | Piedmont Airlines | Jan 2025 – May 2026 |
| Mobile Regional → William P Hobby MOB–HOU | 1 | 70 | 92% | 427 | PSA Airlines Inc. | Jun 2026 – Jun 2026 |
| Mobile Regional → Wichita Dwight D Eisenhower Ntl MOB–ICT | 1 | 72 | 39% | 711 | Sun Country Airlines d/b/a... | Sep 2025 – Sep 2025 |
| Mobile Regional → Laughlin/Bullhead International MOB–IFP | 1 | 94 | 51% | 1,555 | Sun Country Airlines d/b/a... | Feb 2026 – Feb 2026 |
| Mobile Regional → New Castle MOB–ILG | 1 | 179 | 99% | 944 | Allegiant Air | Dec 2025 – Dec 2025 |
| Mobile Regional → Frederick W Smith Intl/Memphis MOB–MEM | 1 | 0 | 0% | 316 | Sun Country Airlines d/b/a... | Nov 2025 – Nov 2025 |
| Mobile Regional → Marsh Harbour MOB–MHH international | 1 | 4 | 50% | 736 | CFM Inc d/b/a Contour... | Jun 2026 – Jun 2026 |
| Mobile Regional → Mobile Regional MOB–MOB | 1 | 0 | 0% | 0 | SkyWest Airlines Inc. | May 2026 – May 2026 |
| Mobile Regional → Louis Armstrong New Orleans International MOB–MSY | 1 | 170 | 94% | 129 | Delta Air Lines Inc. | Mar 2025 – Aug 2025 |
| Mobile Regional → San Antonio International MOB–SAT | 1 | 64 | 84% | 617 | PSA Airlines Inc. | Oct 2025 – Oct 2025 |
| Mobile Regional → St. Louis Lambert International MOB–STL | 1 | 0 | 0% | 568 | Sun Country Airlines d/b/a... | Feb 2026 – Feb 2026 |